Prevention of biofilm formation by quorum quenching
نویسندگان
چکیده
منابع مشابه
Quorum sensing in Acinetobacter: with special emphasis on antibiotic resistance, biofilm formation and quorum quenching
Acinetobacter is an important nosocomial, opportunistic human pathogen that is gradually gaining more attention as a major health threat worldwide. Quorum sensing (QS) is a cell-cell communication system in which specific signaling molecules called autoinducers accumulate in the medium as the population density grows and control various physiological processes including production of virulence ...
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Acinetobacter baumannii is a major human pathogen associated with multidrug-resistant nosocomial infections; its virulence is attributed to quorum-sensing-mediated biofilm formation, and disruption of biofilm formation is an attractive antivirulence strategy. Here, we report the first successful demonstration of biofilm disruption in a clinical isolate of A. baumannii S1, using a quorum-quenchi...
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Background: Previous studies have suggested the quorum sensing signal AI-2 as a potential target to prevent the biofilm formation by Streptococcus mutans, a pathogen involved in tooth decay. Objective: To obtain inhibition of biofilm formation by S. mutans by extracts obtained from the marine bacterium Tenacibaculum sp. 20J interfering with the AI-2 quorum sensing system. Design: The AI-2 inhib...
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Subtilosin, the cyclic lantibiotic protein produced by Bacillus subtilis KATMIRA1933, targets the surface receptor and electrostatically binds to the bacterial cell membrane. In this study, subtilosin was purified using ammonium sulfate ((NH4)2SO4) precipitation and purified via column chromatography. Subtilosin's antibacterial minimum and sub-minimum inhibitory concentrations (MIC and sub-MIC)...
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In the present study, variation among different bacterial strains was observed in the plaques of tobacco chewers (TC) as compared to those from normal persons (non tobacco chewers) (NTC). Bacterial strain J1 (dominant in the plaques of NTC) did not initiate the process of adhesion (biofilm formation) until it appeared to have reached a required population density necessary for the production of...
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ژورنال
عنوان ژورنال: Applied Microbiology and Biotechnology
سال: 2020
ISSN: 0175-7598,1432-0614
DOI: 10.1007/s00253-020-10349-w